Xtalpi 晶泰科技

 
XtalPi_logo.jpg
 

about the company

Xtalpi (https://www.jingtaikeji.com ) is a computing-driven innovation drug research and development technology company, based on cutting-edge computational physics, quantum chemistry, artificial intelligence and cloud computing technology, to provide intelligent drugs for global innovative pharmaceutical companies R&D services.

We have a high-growth innovative leader in the field : co-founded by three Massachusetts Institute of Technology postdoctoral , with cutting-edge technology enabling the pharmaceutical industry ;

We have the strong support of well-known capital : we have received investment from Tencent, Google, Sequoia Capital, China Life, etc. , with a total financing amount of nearly 400 million US dollars

We have a cross-field global expert team : about 70% have a master's degree or above , and there are more than 50 domestic and foreign research doctors . Gather experts in multiple fields such as drug design, computational chemistry, artificial intelligence, cloud computing, etc.

Headquartered in Shenzhen, with branches in Beijing, Shanghai and Boston

We serve the world's top pharmaceutical companies : half of the world's top 20 pharmaceutical companies are customers of Xtalpi Technology . Cumulative accelerate 100+ new drug pipeline , participation in R & D activities 500+ items .

Go alone fast, go far

We urgently call dynamic, dream of fresh blood , and jointly promote the reform of global drug development field !

晶泰科技(https://www.jingtaikeji.com）是一家以计算驱动创新的药物研发科技公司，基于前沿计算物理、量子化学、人工智能与云计算技术，为全球创新药企提供智能化药物研发服务。

我们有高成长性领域的创新领跑者：由三位麻省理工学院博士后联合创立，以前沿科技赋能制药产业；

我们有知名资本的鼎力支持：获腾讯、谷歌、红杉资本、中国人寿等投资，总融资额近4亿美金

我们有跨领域的全球专家团队：硕士及以上学历占比约70%，有50多位国内外科研博士。汇聚药物设计、计算化学、人工智能、云计算等多领域专家

以深圳为总部，并在北京、上海、波士顿设有分部

我们服务全球顶尖药企：全球前20的药企中，半数为晶泰科技客户。累计加速100+新药管线，参与研发活动500+项。

独行快，众行远

我们迫切召唤有活力、有梦想的新鲜血液，共同推动全球药物研发领域的变革！

HIRING

招聘职位1：    人工智能辅助药物设计研究员    

招聘人数预估：      2        

工作地点：      深圳、上海、北京          

岗位描述：（中英文）

岗位职责：

1. 利用最新的机器学习、深度学习、人工智能等算法加速药物开发的进程，包括新靶点的挖掘、小分子结合活性的预测以及先导化合物的优化等；

2. 对相关的数据进行整合和分析，并且参与搭建整个新药研发的计算平台；

3. 密切关注计算化学、云计算和人工智能等前沿技术在药物开发研究中的应用前景。

 任职要求：

1. 硕士或博士学历，应用数学、统计学、计算机科学等专业背景，有计算化学项目经验的优先考虑；

2. 对机器学习算法、神经网络和强化学习等有理论上的知识和实际应用的能力；

3. 有比较完整的人工智能算法开发的项目经验。

Job Responsibilities:

1. Use the latest machine learning, deep learning, artificial intelligence and other algorithms to accelerate the process of drug development, including the exploration of new targets, the prediction of small molecule binding activities, and the optimization of lead compounds; 

2. Integrate and analyze relevant data, and participate in the construction of the entire new drug research and development computing platform;

3. Pay close attention to the application prospects of cutting-edge technologies such as computational chemistry, cloud computing and artificial intelligence in drug development and research.

Job requirements:

1. Master's or doctoral degree, applied mathematics, statistics, computer science and other professional backgrounds, experience in computational chemistry projects is preferred; 

2. Have theoretical knowledge and practical application capabilities for machine learning algorithms, neural networks and reinforcement learning; 

3. Have relatively complete project experience in artificial intelligence algorithm development. 

 

招聘职位2： 计算机辅助药物设计研究员

招聘人数预估：      2       

工作地点：      深圳、北京         

岗位描述：（中英文）

岗位职责：

1.带领团队进行项目调研相关工作，包括文献调研，数据库检索，专利检索，SAR分析，结构分析等方面；

2.利用常规和公司自研的计算机辅助药物设计、人工智能新药研发工具为新药研发项目提供支持；

3.与药物化学和药理药代方面的实验专家协作，提供包括数据解读，SAR分析等方面的支持；

4.能支持多个新药研发项目，和公司内部和外部相关团队一起为项目制定和优化计算模拟策略；

5.跟踪计算机辅助药物设计领域的最新进展和动态，并做出相应的评估。

任职要求：

1.博士学历，有计算机辅助药物设计相关项目经历；

2.熟悉基于结构/配体的药物设计方法，包括分子对接，虚拟筛选，QSAR，药效团模型，分子动力学，结合自由能等;

3.熟悉机器学习和AI药物设计方法；

4.熟悉Linux操作系统，能熟练运用脚本/程序分析模拟结果；掌握一门编程语言(Python, Java, C++, C, Fortran等)；

5.具有良好的英语阅读和书写能力，能够熟练查阅相关领域文献。

具有以下经验优先考虑：

1.熟悉各种疾病的机理和最新的药物研发进展；

2.先导化合物优化项目经验；

3.熟悉药物化学及结构相关知识；

4.熟练掌握Python等编程语言。

Job Responsibilities:

1. Lead the team to carry out project research related work, including literature research, database search, patent search, SAR analysis, structural analysis, etc .;

2. Use conventional and self-developed computer-aided drug design and artificial intelligence new drug R&D tools to provide support for new drug R&D projects;

3. Cooperate with experimental experts in medicinal chemistry and pharmacology and pharmacology, and provide support including data interpretation and SAR analysis ;

4. Can support multiple new drug research and development projects, and work with the company's internal and external related teams to formulate and optimize calculation simulation strategies for the project ;

5. Track the latest developments and trends in the field of computer-aided drug design, and make corresponding assessments.

Job requirements:

1. Doctor degree, with experience in computer-aided drug design related projects;

2. Familiar with structure / ligand-based drug design methods, including molecular docking, virtual screening, QSAR , pharmacophore models, molecular dynamics, binding free energy, etc .;

3. Familiar with machine learning and AI drug design methods;

4. Familiar with the Linux operating system, able to use scripts / programs to analyze simulation results; master a programming language (Python, Java, C++, C, Fortran, etc. ) ;

5. Have good English reading and writing skills, and be able to read documents in related fields proficiently .

The following experience is preferred:

1. Familiar with the mechanism of various diseases and the latest drug development progress;

2. Lead compound optimization project experience;

3. Familiar with medicinal chemistry and structure related knowledge ;

4. Proficiency in programming languages ​​such as Python .

 

招聘职位3： DMPK研究员

招聘人数预估：      2       

工作地点：      深圳         

岗位描述：（中英文）

工作职责：

1. 负责体外ADME实验和PK样品检测实验平台的建立和验证；

2. 负责新化合物的早期体外和体内DMPK试验的探索性研究，包括完成小分子化合物药代实验方案的制定和定量分析方法的建立和测试；

3. 负责及时发现、解决DMPK实验进程中可能出现的技术问题以确保项目顺利进行及相关文献资料的收集与分析；

4. 负责DMPK申报资料的整理撰写和审阅；

5. 负责仪器的日常维护与验证，起草仪器验证文件、仪器标准操作规范，书写相关SOP，实验记录和实验报告。

任职要求：

1. 药物代谢或药物分析等相关专业，硕士及以上学历；

2. 熟练掌握动物试验，CaCO2，肝细胞稳定性及代谢物鉴定优先考虑；

3. 对液质联用LC/MS/MS操作或生物样品定量分析经验者；有实验平台建立、CRO工作经验者经验优先；

4. 能独立设计，完成和分析体内外DMPK实验；撰写相关专业报告；具有同时开展多个项目并合理规划项目进度的能力；

5. 熟练使用LC/MS等分析仪器；熟悉分析仪器的使用维护；具有较强的实验动手能力和解决实际问题的能力；

6. 了解创新药物研发流程；熟悉非临床药代动力学研究常用的体内、外研究方法；了解CFDA和ICH新药研究相关指导原则；

7. 良好的英语听说读写能力，有独立思考，勇于创新并解决问题的能力。工作认真刻苦，对工作有强烈的责任感；良好的团队协作精神。

Job responsibilities:

1. Responsible for the establishment and verification of in vitro ADME experiments and PK sample detection experimental platforms;

2. Responsible for the exploratory research of early in vitro and in vivo DMPK tests of new compounds , including the completion of the formulation of small molecule compound pharmacokinetic experiments and the establishment and testing of quantitative analysis methods;

3. Responsible for promptly discovering and solving technical problems that may arise in the process of DMPK experiment to ensure the smooth progress of the project and the collection and analysis of relevant documents;

4. Responsible for the compilation and review of DMPK application materials; 

5. Responsible for the daily maintenance and verification of the instrument, drafting instrument verification documents, instrument standard operating specifications, writing related SOPs , experimental records and experimental reports. 

Job requirements:

1. Major in drug metabolism or drug analysis, master degree or above;

2. Familiar with animal experiments, CaCO2 , liver cell stability and metabolite identification are preferred;

3. Experience in LC/MS/MS operation or quantitative analysis of biological samples; experience in experimental platform establishment and CRO work experience is preferred;

4. Ability to independently design, complete and analyze in vivo and in vitro DMPK experiments; write related professional reports; have the ability to carry out multiple projects at the same time and plan the project schedule reasonably;

5. Familiar with the use of analytical instruments such as LC/MS ; familiar with the use and maintenance of analytical instruments; have strong experimental hands-on ability and ability to solve practical problems;

6. Understand the research and development process of innovative drugs; be familiar with in vivo and in vitro research methods commonly used in non-clinical pharmacokinetic research; understand the relevant guidelines of CFDA and ICH new drug research;

7. Good English listening, speaking, reading and writing skills, independent thinking, creative and problem-solving skills. Work hard and have a strong sense of responsibility; good teamwork spirit.

 

招聘职位4：   冷冻电镜实验研究员   

招聘人数预估：      1       

工作地点：      深圳         

岗位描述：（中英文）

岗位职责：

1.    制备电镜实验样品；

2.    收集电镜实验数据；

3.    从实验数据解析晶体结构；

4.    撰写实验记录和分析报告；

5.    参加电镜基本的日常维护工作。

 任职要求：

1.   博士学历，物理、化学、材料或者结构生物学等相关专业；

2.    有2年以上电子显微镜实验经验，熟悉生化实验室基本实验操作；

3.    有耐心，做事认真仔细，乐于沟通，具有良好的责任心及团队合作精神。

Job Responsibilities:

1. Preparation of experimental samples for electron microscopy ;   

2. Collect experimental data of electron microscope ;   

3. Analyze the crystal structure from experimental data ;   

4. Write experiment records and analysis reports ;   

5. Participate in the basic daily maintenance of the electron microscope.   

Job requirements:

1. Doctor degree, major in physics, chemistry, materials or structural biology ; 

2. There are 2 experimental electronic microscope more years experience, familiar with the basic biochemistry laboratory experimental operation ;   

3. Be patient, work carefully and carefully, be willing to communicate, have a good sense of responsibility and teamwork spirit.   

 

 

招聘职位5：   晶型实验项目经理   

招聘人数预估：      1       

工作地点：      深圳         

岗位描述：（中英文）

岗位职责：

1、负责与BD/客户进行项目沟通；

2、负责组织讨论项目的解决方案以及控制项目的实施过程；

3、负责进行项目规划、主要包括项目时间、成本、质量三方面规划；

4、负责控制项目进度、成本、质量；

5、负责整理、分析、发布项目各阶段对外报告。

任职要求：

1、全日制博士学历，物理、化学、药学相关专业；

2、英语流利，可以与外国客户直接用英语沟通；

3、有小分子化药制剂、结晶、合成实验的经验；

4、具有较强的对业务的理解能力和学习能力；

5、积极主动，具备良好的规划、沟通、协调、风险管控能力；

6、有较强的责任心，可以对项目的质量负责。

Job Responsibilities:

1. Responsible for project communication with BD/ customers;

2. Responsible for organizing and discussing project solutions and controlling the implementation process of the project;

3. Responsible for project planning, including three aspects of project time, cost and quality planning;

4. Responsible for controlling project schedule, cost and quality;

5. Responsible for collating, analyzing, and publishing external reports at all stages of the project.

Job requirements:

1. Full-time doctoral degree, major in physics, chemistry, pharmacy;

2. Fluent in English, can communicate directly with foreign customers in English;

3. Experience in small molecule chemical preparations, crystallization and synthesis experiments;

4. Have a strong business understanding and learning ability;

5. Proactive, with good planning, communication, coordination, risk management and control capabilities;

6. Have a strong sense of responsibility and be responsible for the quality of the project.

  

招聘职位6：   HR管培生（偏招聘）   

招聘人数预估：      1       

工作地点：      深圳         

岗位描述：（中英文）

岗位职责：

1、招聘工作的执行，包括发布职位、简历筛选、面试邀约、面试接待等；

2、编写招聘文案，充分利用各种招聘渠道发布招聘信息；

3、招聘渠道的日常维护和拓展；

4、参与校园招聘、社会招聘项目；

5、良好的亲和力、有耐心、积极主动，责任心强；

6、领导临时交待的其他工作。

任职资格：

1、人力资源、企业管理等专业，21届应届生；

2、熟练使用word、Excel、photoshop等办公软件；

3、有较强的文字写作能力，有微信公众号运营经验优先；

4、沟通能力良好，执行力强，有社团等学生工作经验的优先；

5、热爱HR工作，愿意在此领域发展，有强烈的学习意愿；

6、有国外留学经历或英文能力突出者优先。

Job Responsibilities:

1. Implementation of recruitment work, including job posting, resume screening, interview invitation, interview reception, etc.;

2. Compile recruitment copy and make full use of various recruitment channels to release recruitment information;

3. Daily maintenance and expansion of recruitment channels;

4. Participate in campus recruitment and social recruitment projects;

5. Good affinity, patience, initiative, and strong sense of responsibility;

6. Other tasks temporarily assigned by the leader.

Job Requirements:

1. Majors in human resources, business management, etc., the 21st freshman;

2. Proficiency in using word , Excel , photoshop and other office software;

3. Strong writing ability, experience in WeChat public account operation is preferred;

4. Good communication skills, strong execution, working experience in clubs and other students is preferred;

5. Love HR work, willing to develop in this field, and have a strong willingness to learn;

6. Those with overseas study experience or outstanding English ability are preferred.

Company URL: https://www.jingtaikeji.com

Work-Types offered: Full time

Class Years looking for: 2020/2021

Citizenships looking for: all

Degrees looking for: Bachelor of Science (B.S.), Master of Science (M.S.), Medical Doctor (M.D.), B.Tech